Neuroendocrinology of pyridoxine deficiency
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چکیده
منابع مشابه
Neuroendocrinology of pyridoxine deficiency.
Dihydroxyphenylalanine decarboxylase and 5-hydroxytryptophan decarboxylase respectively have high and low affinities for pyridoxal phosphate. In the pyridoxine-deficient animal, hypothalamic serotonin content is significantly reduced without any change in catecholamine levels. Hypothalamic neurotransmitters affect the hypothalamo-pituitary-end organ axes. Specifically, the decrease in hypothala...
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Isoniazid-induced deficiency of pyridoxine (vitamin B6) is reportedly not uncommon in adults but rare in children. In the present study, 38 children had serum levels of pyridoxine tested while receiving therapy with isoniazid. A biologic assay using the protozoan Tetrahymena thermophila determined pyridoxine status after 2 to 18 months of therapy with isoniazid. Five children (13 percent) were ...
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Cer ta in an t ime tabo l i t e s are capable of caus ing specific effects which can be dupl ica ted in some instances by a n acu te d i e t a ry deficiency of the cor responding metabol i te . F o r example, leukopenia can be induced in exper imenta l an imals by feeding a die t lacking folic acid or by t r e a t m e n t wi th a folic acid an t agon i s t (11, 19). E v e n though the use of de...
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ژورنال
عنوان ژورنال: Neuroscience & Biobehavioral Reviews
سال: 1988
ISSN: 0149-7634
DOI: 10.1016/s0149-7634(88)80040-x